The Menopause Biotype DNA Test

(Female Regenerative Health DNA Report)

Understand the biology behind your symptoms, your transitions, and your long-term health, so you can make confident, personalized decisions during menopause and beyond.

The Menopause Biotype Genetic Test is a revolutionary tool designed to inform women as they navigate the unique journey of menopause. This test helps identify individual biotypes to predict menopausal symptoms, potential disease risks, and potential effective treatments and lifestyle interventions tailored to each woman's specific needs.

The FRH Report is a comprehensive genomic analysis spanning 19 clinically curated categories — from Estrogen Receptor Sensitivity and Cortisol Regulation to Hormone Metabolism, Menopause Onset, and Sleep & Circadian Regulation. Across these categories, 132 genetic variants are analyzed and mapped to the biological pathways that shape how each patient metabolizes, signals, and responds to hormones. Every variant is classified by pathogenicity and grounded in peer-reviewed research — a layered view of the forces driving a patient’s hormonal health.

A pathway-driven genomic blueprint that translates YOUR unique biology into protocol-ready clinical insight for female hormone, regenerative, and wellness care you can share with your providers (along with your other biomarker tests, etc. from your EMR) to devise a more precise menopause management plan.

We test:

Why This Test Matters

Menopause is universal. How you experience it is not.

Some women glide through menopause with minimal disruption. Others face intense symptoms that impact sleep, work, relationships, and self-confidence.

These differences are not random — they are rooted in biology. 

The Menopause Biotype DNA Test identifies genetic patterns that may influence:

• Hormone metabolism and receptor sensitivity
  
• Inflammation and stress pathways
  
• Sleep and circadian rhythm regulation
  
• Metabolism and weight changes
  
• Temperature regulation
• Cognitive shifts, mood variability, and emotional load
• Long-term patterns in bone, brain, and cardiovascular health

By understanding your genetic tendencies, you gain a clearer picture of what your body needs and how to support it as it changes.

How this Test is Different

Most genetic tests deliver a flat list of SNPs with little context. The FRH Report takes a pathway-driven approach, mapping how variants interact across interconnected biological systems — from steroid hormone synthesis to neurotransmitter reward pathways. BIOS dynamically interprets 132 variants using AI/ML into 19 clinically curated categories built specifically for female regenerative health. Every finding is grounded in 1,145+ peer-reviewed citations — an evidence base matching the rigor of clinical training.

What You Receive

A personalized, science-informed roadmap through menopause

Your Menopause Biotype report includes:

• Your personalized menopause biotype
• A clear summary of your genetic tendencies and how they may shape your experience across perimenopause, menopause, and the years that follow.
• Hormone processing insights
• Understand how your body may metabolize or respond to estrogen, progesterone, and other hormones — and what that means for symptom intensity and therapy considerations.
• Symptom likelihood and pattern analysis
• Clarity around genetic susceptibilities related to hot flashes, night sweats, mood changes, cognitive fog, sleep problems, weight shifts, and more.
• Long-term health markers
• Science-backed insight into bone density tendencies, cardiovascular markers, and neurological resilience relevant to midlife transitions.
• Lifestyle and nutrition strategies
• Clear, simple steps aligned with your biology to support energy, sleep, metabolism, and mood.
• Questions and guidance for your clinician
• A structured section to support more informed conversations about HRT, non-hormonal options, and protective long-term wellness strategies.

Who This Test Is For

For women who want answers, not more guessing

This test is ideal if:

• You are 38–60 and noticing changes in mood, sleep, energy, or weight
  
• Your labs say “normal,” but you feel anything but
  
• You want to understand why your experience feels the way it does
  
• You want to take a proactive, personalized approach
  
• You are considering HRT and want clarity before making a decision
• You are already on treatment and want to understand your body better
  

How It Works

Step 1: Order your biotype DNA test

Your kit arrives with everything you need for a quick cheek swab.

Step 2: Collect and return your DNA sample

No blood draw, no appointments. Your sample is processed in a CLIA- and CAP-certified lab for quality and accuracy. 

Step 3: Receive your personalized biotype report

In about three to four weeks, your secure digital results will be ready. They explain what your biology reveals about menopause or andropause — and outline actionable steps aligned with your unique needs.

See Inside the Report

Important Notes

Rephase offers clarity, not diagnosis.

Your test will not:

• Diagnose disease
• Replace hormone labs or medical evaluation
• Guarantee specific outcomes

It will give you a clearer understanding of your biology — the foundation for better decisions, better conversations, and a more empowered menopause journey. You will be able to layer this test as your foundation or roadmap of YOUR biology and DNA over other biomarker tests (hormones, etc.) that give snapshots in time; to show a clearer and more precise pathway to hormone treatments that are more custom to your needs.